2013年生物科学论?第二十二朞/h1>
报告题目：Insights from the microRNA behaviors in plants
人： ?nbsp; 副研究员（中国农业科学院
报告时间?1?1日（星期一 下午15:00
报告地点：生物楼201宣/P>
摘要:
As the most important class of small silencing RNAs (sRNAs), microRNAs (miRNAs) are canonically considered to be 20-22 nucleotides (nt) in length and guide targets regulation via mRNA degradation or translation inhibition. A class of 24-nt long miRNAs has been characterized as modulators through DNA methylation for gene expression in rice, implying a more complicated miRNA population in plants. Our recent study found a Pooideae-specific miRNA that targets florigen genes and regulates flowering time in Brachypodium under different daylength, suggesting that both conserved and non-conserved miRNAs play critical roles in plant growth and adaptation to the environments.
研究领域：植物小分子RNA作用机制和功能研
教育背景
1999.9-2003.7 山西农业大学 本科
2003.9-2006.7 南京农业大学 硕士
2007.9-2010.6 北京生命科学研究所 北京师范大学 博士
工作经历
2006.7-2007.8 北京生命科学研究所 研究助理
2010.7- 2010.10 北京生命科学研究所 博士
2010.11- 2011.8 德国马普发育生物学研究所 博士
2011.9-至今 中国农业科学院作物科学研究所 副研究员
部分代表文章:
1) Wu. L*., Liu. D., Wu. J., Qin.Z., Zhang.R., Li, A., Zhai. W., and Mao. L* (2013) Regulation of FLOWERING LOCUS T by a microRNA inBrachypodium distachyon. The Plant Cell. In press
2) Wu. L * (2013) DICER-LIKE1 processed trans-acting siRNAs mediate DNA methylation: Case study of complex small RNA biogenesis and action pathways in plants. Plant Signaling and Behavior, volume 8, issue 1
3) Wu. L*., Mao L., and Qi Y. (2012) Roles of DICER-LIKE and ARGONAUTE Proteins in TAS-Derived Small Interfering RNA-Triggered DNA Methylation. Plant Physiology, 160: 990-999
4) Wu. L., Zhou, H., Zhang, Q., Zhang, J., Ni, F., Liu, C., and Qi, Y. (2010) DNA methylation mediated by a microRNA pathway. Molecular cell, 38, 465-475 (Cover story) this work was featured in Cell, 141: 556, 2010.
5) Wu. L., Zhang Q., Zhou H., Ni F., Wu X., Qi Y. (2009) Rice microRNA effector complexes and targets. The Plant Cell, 21:3421-3435
欢迎各位老师，同学参加！
生物科学与技术学
2013?1?
